A one-pot preparation of isothiocyanates from amines using two phosgene substitutes : bis-(trichloromethyl) carbonate and trichloromethyl chloroformates

A series of isothiocyanates have been prepared in high yields in a one-pot reaction from commercial amines and carbon disulfide under mild conditions using bis(trichloromethyl)carbonate (BTC) and trichloromethyl chloroformate (TCF) as reagents in the presence of base.