Sphingosine kinase 2 supports the development of BCR/ABL-independent acute lymphoblastic leukemia in mice
2018
Background
Sphingosine kinase (SphK) 2 has been implicated in the development of a range of cancers and inhibitors of this enzyme are currently in clinical trial. We have previously demonstrated a role for SphK2 in the development of acute lymphoblastic leukemia (ALL).
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KQI