Derivatives oxipropanol aryl amines, their preparation process and their applications.

1997 
The invention relates to derivatives of ARILOXIPROPANOLAMINA having at least an antidiabetic and antiobesity activity as well as their methods of preparation and their applications, PARTICULARLY AS DRUGS AND VETERINARY MEDICINE HUMAN AND AS ANIMAL FOOD ADDITIVE. These derivatives correspond to formula (I), wherein: R 2 represents one of the following groups: -CH 2 -, -CH 2 - CH 2 CH (CH 3) - CH 2 -, -CH (CH 3 ) = CH, C (CH 3) SUB, 2 - CH 2 - or a bond Q represents: (i) a radical FE NILE 3,4 - disubstituted alkylene alkylenedioxy DETERMINING WITH phenyl radical, UNIT benzodioxan unsubstituted, A UNIT benzodioxol unsubstituted OR benzodioxol 2 UNIT - sUBSTITUTED, (ii) a phenyl radical 3 and / or 4 substituted by a 0 - (CH 2) X - COOR 5, (iii) a condensed polycyclic hydrocarbon comprising at least TWO CYCLES CONDENSED, (IV) cYCLIC SYSTEM hydrocarbon, optionally LINKED AND FORMED, and constituting a cycloalkane comprising 1,2 or 3 cycles.
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