Stereoselective Nucleophilic Addition of Chiral Lithium Enolates to (N-Tosyl)imines: Enantioselective Synthesis of β-Aryl-β-amino Acid Derivatives.
2010
Abstract Nucleophilic addition of the chiral lithium enolates of (S)-(−)-4-benzyl-2-oxazolidinone acetamide with N-tosyl arylaldehyde imines gives β-aryl-β-amino acid derivatives in good yields and excellent diastereoselectivity.
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