The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes

María Esteban-Torres,Yanaisis Álvarez,Iván Acebrón,Blanca de las Rivas,Rosario Muñoz,Gert-Wieland Kohring,Ana Maria Roa,Mónica Sobrino,José M. Mancheño

The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes

2012

María Esteban-Torres
Yanaisis Álvarez
Iván Acebrón
Blanca de las Rivas
Rosario Muñoz
Gert-Wieland Kohring
Ana Maria Roa
Mónica Sobrino
José M. Mancheño

JMM and RM thank the Ministerio de Ciencia e Innovacion for their research grantsBFU2010-17929, CSD2006-00015 and AGL2011-22745, CSD2007-00063 FUN-C-FOOD and Comunidad de Madrid S2009/AGR-1469, respectively.

Keywords:

Galactitol-1-phosphate 5-dehydrogenase
Dehydrogenase
Metal Binding Site
Oxidoreductase
Biochemistry
Crystal structure
Escherichia coli
Galactitol
Nitrilotriacetic acid
Stereochemistry
Chemistry
NAD+ kinase
Tagatose
Protein–protein interaction
Recombinant DNA

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