Extrasystoles: adverse effects of the first postextrasystolic contraction

Aim . To determine the changes of parameters of heart biomechanics and kinetics of arteries, to reveal the adverse events of first post-extrasystolic contraction. Materials and methods . In our investigation we included 286 patients. We excluded all the main traditional risk factors of the atherosclerosis. All the patients were branched into two main groups in accordance to the quantity of extrasystoles per 24 hours: I group – less than 3000, II group – more than 3000 extrasystoles per 24 hours. We took the data about complaints, anamnesis, made laboratory and instrumental investigations to reveal the character and severity of atherosclerotic process. Results . We determined that the atherosclerotic process was more advanced and more often in the group II. Also the atherosclerosis was more severe in patients with extrasystoles in the phase of cardiocycle before opening of the mitral valve and before the transmitral blood flow peak. The parameters (acceleration, speed, power, work) that were calculated by apexcardiography and sphygmography increased with the further tendency: if earlier extrasystole appears in cardiocycle, than more changes were observed. Conclusion . The first post-extrasystolic contraction causes the increase of all parameters of heart biomechanics and kinetics of vessels and can be an additional factor of progressing of atherosclerosis.