Positive correlation between daily changes of initial distribution volume of glucose and cardiac output following subtotal esophagectomy

We have reported that the initial distribution volume of glucose (IDVG) reflects the central extracellular fluid volume status and correlated with cardiac output following major surgery. In clinical practice we are using IDVG as an indicator of cardiac preload to predict hypovolemia or fluid refilling phase following major surgery. IDVG is an intermittent measurement parameter and its rather time consuming procedure limits frequent measurements of IDVG. In this study, to investigate whether or not continuous cardiac output (CO) monitoring could be used as a clinical alternative of IDVG to estimate the changes in cardiac preload, we examined a correlation between changes in CO and IDVG in sedated, mechanically ventilated postoperative patients.