A Continuous Static‐Mixer‐Based Reactor for Preparing Calcium Phosphate Bioceramics

The common methods for synthesizing calcium phosphates include solid-state reaction, hydrothermal, sol–gel, and wet precipitation. The purpose of this study was to prepare various calcium phosphate bioceramics through a continuous reactor equipped with a static mixer. The precursors, amorphous calcium phosphate (ACP), and poor crystal hydroxyapatite (PC-HAp) were prepared using calcium and phosphate ion-containing solutions by adjusting the pH and the [Ca]/[P] input ratio. The phase transformation from precursors to HAp, alpha-tricalcium phosphates (α-TCP), beta-tricalcium phosphate (β-TCP), or biphasic calcium phosphate (BCP) was dependent on the sintering temperature.