Is antibiotic prophylaxis necessary in patients on chronic dialysis and with recurrent endocarditis

: The authors present a group of 77 patients with chronic dialysis treatment during the period from 1/92 to 4/95 with regard to the prevalence of infectious endocarditis. This disease was detected in 8 instances in 6 patients whereby one patient had three relapses. In 75% staphylococci were the infectious agent. The main risks of the disease are according to the authors impaired immunity, repeated cannulation, degenerative valvular changes. In the conclusion the authors state that the risk of developing infectious endocarditis and relapses of the disease can be reduced by careful diagnosis and antibiotic therapy. The authors do not consider lifelong antibiotic prophylaxis of these patients necessary.