Нарушения синхронизации кровообращения и дыхания при гиперкапнической дыхательной пробе и умеренных физических нагрузках у пациентов c пульмонологической патологией

Relevance .The comprehensive assessment of cardiorespiratory coupling (CRC) for the diagnosis of functional adaptation in pulmonological patients is presented. The objective of the study was to test the complex criteria of CRC for objective differential diagnosis of individual adaptive reactions of pulmonological patients. Methods and materials . 30 volunteers without verified pathology and 31 patients with restrictive and obstructive disorders were examined. All subjects underwent physical examination with traditional routine method using spiroarteriocardiorhythmography (SACR) at rest and during performing functional tests with hypercapnia and moderate physical exercise. Results . We proposed the methodology of integrated assessment of multicomponent system of CRC, which increases the diagnostic precision of SACR in the tasks of predicting the adaptive defects of the organism at different pulmonary syndromes. Conclusion . Breathing with a fixed frequency normalizes the regulation of CRC, both in healthy and pulmonological patients. Moderate physical activity (80 W) modifies the indicators of CRC in pulmonological patients in comparison with the control group statistically due to disorders of the heart rate and circulation. During moderate physical activity, stroke volume (SV) statistically decreases in patients differently: SV were significantly lower in the group with obstructive disorders than in the group with non-obstructive disorders.