New ideas - Transplantation A new disposable perfusion machine, nuclear magnetic resonance compatible, to test the marginal organs and the kidneys from non- heart-beating donors before transplantation

This article is the first report about our new hypothermic pulsatile perfusion machine (HUG’s HPP-machine) for kidney perfusion. This machine will be used for P NMR spectroscopy. The aim is to obtain scores of viability of marginal kidneys and those from non-heart31 beating donors (NHBD) before transplantation using HPP as it has been demonstrated necessary in these situations. The most predictable test is the ratio of phosphomonoester on inorganic phosphorus (PMEyPi) that can be obtained from P spectroscopy. The machine has been 31 built to allow perfusion of kidneys in the range of that performed with the traditional Belzer, Mox-Waters machines and others, but compatible with the magnetic fields of the MRI apparatus used for P NMR spectroscopy. In this publication, the technical aspects of this 31