5-deuterated compounds trideuterometil-6-methyl-2-thioxo-2,3-dihydropyridin-4 (1H) -one and preparation method thereof.

5-deuterated compounds trideuterometil-6-methyl-2-thioxo-2,3-dihydropyridin-4 (1H) -one and preparation method thereof. # The invention defined deuterated compounds of formula (I) # ** FIGURE ** # in which: #R {sub, 1}, {R sub 2} represent independently a hydrogen atom or an alkyl group C {sub, 1} -C {sub, 4}, substituted ? # a group oR sub {4}, R {sub, 4} a hydrogen atom or an alkyl group C {sub, 1} -C {sub, 3} substituted phenyl; # a group NR {sub? , 5} R {sub, 6}, R {sub, 5} and R {sub, 6} independently a hydrogen atom, or an alkyl group C {sub, 1} -C {sub, 3}, tosyl or mesyl;? # a group SR {sub, 7}, R {sub, 7} a hydrogen atom or an alkyl group C {sub, 1} -C {sub, 3}; # a group OCOR {? sub, 8}, where {R sub 8 alkyl group} C {sub, 1} -C {sub, 3} or phenyl; I # or a halogen atom; and # D represents deuterium. # The invention also defines a method for preparing such deuterated compounds, a pharmaceutical composition comprising, and the use thereof in the pharmaceutical and analytical field.