Design, Synthesis and Antitubercular Evaluation of Novel 2‐Substituted‐3H‐benzofuro Benzofurans via Palladium—Copper Catalyzed Sonogashira Coupling Reaction.

Thirumal Yempala,Jonnalagadda Padma Sridevi,Perumal Yogeeswari,D. Sriram,Srinivas Kantevari

Design, Synthesis and Antitubercular Evaluation of Novel 2‐Substituted‐3H‐benzofuro Benzofurans via Palladium—Copper Catalyzed Sonogashira Coupling Reaction.

2014

Thirumal Yempala
Jonnalagadda Padma Sridevi
Perumal Yogeeswari
D. Sriram
Srinivas Kantevari

Compound (Ve) is found to exhibit the best in vitro anti-mycobacterial activity against Mycobacterium tuberculosis H37Rv with lower cytotoxicity and good therapeutic index.

Keywords:

Mycobacterium tuberculosis H37Rv
Copper
Cytotoxicity
Therapeutic index
Palladium
Sonogashira coupling
Chemistry
Catalysis
Organic chemistry
copper catalyzed
design synthesis

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations