Antidotal Properties of Crude Penicillium notatum Filtrate

Summary1. The in vitro results on the antidotal factor reported by Ramon, et al. are essentially corroborated.2. This antidotal agent is dialyzable.3. The antidotal activity is inactivated in the presence of blood.4. No in vivo therapeutic activity against tetanus toxin or pertussis endotoxin could be demonstrated.