The production method and the patch of the patch

A method of manufacturing a patch comprising a support layer and an adhesive layer, diacetate alkali metal salts, drug and a non-aqueous adhesive base, the molar ratio (drug and the diacetate alkali metal salt and the drug moles: diacetate moles of alkali metal salt) 1: 0.5 to 1: comprising the step of forming the pressure-sensitive adhesive layer using an adhesive layer composition obtained by mixing such that 15 the method of the patch.