Random antral follicle count performed on any day of the menstrual cycle has the same predictive value as AMH for good ovarian response in in vitro fertilisation cycles.

Abstract Objective To determine whether the predictive value of AFC for ovarian response to stimulation for IVF depends on the day of the menstrual cycle when ultrasound is performed. Methods 410 women undergoing their first IVF cycle were included. All the women had AFC performed twice. The first measurement, random AFC (r-AFC), was performed during the fertility workup whatever the day of their menstrual cycle. Three groups were constituted according to the period of ultrasound performance: at early follicular phase i.e., day 1 to day 6 (eFP-AFC); at mid follicular phase i.e., day 7 to 12 (mFP-AFC) and at luteal phase i.e., day 13 or after (LP-AFC). A second AFC measurement was performed before the start of the ovarian stimulation (SD1-AFC). AMH dosing was done in the early follicular phase. Results Random AFC (r-AFC) was correlated to AMH (r=0.69; p Conclusion AFC is strongly correlated with AMH and highly predictive of good ovarian response during the whole menstrual cycle.