[Normal value and reference value range of brachial-ankle pulse wave velocity among Kailuan study population].

Objective: To establish the normal and reference values of brachial-ankle pulse wave velocity(baPWV) based on Kailuan study population. Methods: There were 22 622 staffs of Kailuan Group who underwent 2010 to 2015 health check-up and baPWV measurement. Data of 20 622 staffs were analyzed after excluding 2 000 staffs due to incomplete data. Of these, 9 109 normal individuals were selected for final analysis of normal and reference values for baPWV after excluding 8 788 staffs who had myocardial infarction, stroke, diabetes, hypertension history, treated by either anti-hypertensive or lipid-lowering drugs, and 2 725 smoker. Results: (1)Age, height, weight, baPWV, systolic pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, estimated glomerular filtration rate, total cholesterol, triglyceride, high density lipoprotein cholesterol, sensitivity C-reactive protein, fasting blood glucose were significant difference between male and female population.(2) In male population, baPWV (mean(rang of 95%)) were 1 248(933-1 564) cm/s for age<30 years, 1 345(995-1 696) cm/s for 30-39 years, 1 407(1 007-1 807) cm/s for 40-49 years, 1457(987-1 927) cm/s for 50-59 years, 1 589(966-2 213) cm/s for 60-69 years, 1 898(1 018-2 778) cm/s for age≥70 years; in female population, baPWVv(mean(rang of 95%)) were 1 080(815-1 344) cm/s for age<30 years, 1 162(845-1 480) cm/s for 30-39 years, 1 264(911-1 618) cm/s for 40-49 years, 1 386(1 004-1 768) cm/s for 50-59 years, 1 581(967-2 196) cm/s for 60-69 years, 1 874(1 288-2 459) cm/s for age≥70 years. Conclusion: Normal value and rang of baPWV are different in different age and gender among Kailuan study population. Clinical Trail Registry Chinese Clinical Trail Registry, ChiCTR-TNRC-11001489.