Comparative study of complications of modified radical mastectomy and breast conservation therapy in early invasive breast cancer
2019
Background: All early breast cancer patients admitted in surgery department were distributed in MRM and BCS groups. All operated cases of early breast cancer in Dept. of Surgery, Amaltas Institute of Medical Sciences, Dewas. The study will include prospective cases 1 year from June 2017 to June 2018. Method: In all MRM group patients all breast tissue, skin, nipple areola complex and level 1, 2, 3 lymph nodes removed. In all BCS group patients lump was removed with an envelope of normal appearing breast tissue. In all resected specimens free surgical margin was ensured via histopathology reports. Patients were reviewed in early post operative period for complications and followed at the end of 1st, 3rd, 6th and 12th month for recurrence. Result: In MRM group two patients developed Seroma formation and one developed Marginal Necrosis. In BCT group one patient had Seroma formation. Complications were present in 20% of MRM group (3 out of 15 cases), while they were absent in 80% (12 out of 15). However, in the BCS group, complications were present in 6.66% cases only (1 out of 15 cases), while were absent in 93.33% (14 out of 15). P value by statistical analysis being 0.283, the difference being statistically insignificant. Recurrence were present in 6.66% of MRM group (1 out of 15) while they were absent in 93.34 % (14 out of 15). However in BCS group recurrence were present in 6.66 % (1 out of 15) and were absent in 93.34% (14 out of 15). P value by statistical analysis being 1, the difference being statistically insignificant. Conclusion: There is no significant difference in the recurrence rate, whether the patient had undergone BCS or MRM based on our short term follow-up. However a delay long term follow-up is required.
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