Confocal Visible/NIR Photoacoustic Microscopy of Early-stage Tumor with Structural, Functional and Nanoprobe Contrasts

We report fiber-based confocal visible/near-infrared optical-resolution photoacoustic microscopy that can image tumor microvasculature, oxygen saturation, and nanoprobes in a single scanning. It offers a new tool for early detection of tumors with multiple contrast modes.