Age-Related Changes in Alpha-Adrenoceptor Mediated Blood Pressure in the Rat: Relationship between the Potency for Phenylephrine and the Maximum Number of Binding Sites

Katsuo Koike,Mitsutoshi Satoh,Saburo Kanai,Hiroshi Ohtsuki,Issei Takayanagi

Age-Related Changes in Alpha-Adrenoceptor Mediated Blood Pressure in the Rat: Relationship between the Potency for Phenylephrine and the Maximum Number of Binding Sites

1996

Katsuo Koike
Mitsutoshi Satoh
Saburo Kanai
Hiroshi Ohtsuki
Issei Takayanagi

To study the effects of aging on the blood pressure potency of phenylephrine, 6-, 10- and 40-week-old rats were used. In anesthetized rats, the potency (pD2 value) of phenylephrine on the b

Keywords:

Diabetes mellitus
Dissociation constant
Phenylephrine
Potency
Endocrinology
Alpha adrenoceptor
Internal medicine
Blood pressure
Thoracic aorta
Binding site
Chemistry
contractile response
age related

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