Влияние паров толуола на некоторые гистоморфометрические параметры интракортикальных нефронов почек крыс старческого возраста

The influence of toluene inhalation on histomorphometric parameters of renal nephrons in rats of senile age period was researched. After 60 days of impact to toluene vapor, the square of glomerulus was lower than the control data by 5.29%, and capsular lumen - higher by 22.84%. Diameters of proximal convoluted tubules and their lumen were higher than the control data by 7.26% and 18.84%, and the height of epithelium was lower by 5.97%, diameters of distal convoluted tubules and their lumen were higher than the control data by 8.25% and 13.89%, and the height of epithelium was not significantly changed. During the period of readaptation after toluene inhalation the recovery of structural-functional state of intracortical nephrons was very slow in senile rats. The usage of thiotriazoline as a possible corrector against the background of toluene inhalation was more effective than the usage of echinacea purpurea.