ISOINDOLINOTRIAZOLE DERIVATIVES: SYNTHESIS BY THE AZIDE-ALKYNE CYCLOADDITION CLICK CHEMISTRY
2014
A novel series of isoindolinotriazole derivatives with different substituents in the triazole moiety were synthesized via copper-catalyzed cycloaddition (CuAAC) click chemistry between 2-( meta - or para -ethynylphenyl)-4,6-dimethoxyisoindolin-1-ones and several azides. The synthesized triazoles were characterized by IR, 1 H NMR, 13 C NMR and mass spectral techniques.
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