Acromegaly with Osteoarthropathy

We investigated 7 cases of acromegaly with osteoarthropathy. In 4 cases of these, symptoms of osteoarthropathy occurred at early phase of acromegaly and preceded the diagnosis of acromegaly. Arthropathy of peripheral joints was same as conditions of osteoarthrosis and it's osteoarthritic changes such as osteophyte were obvious compared with their age. About changes in spine, symptoms due to compression by posterior elements presented as lumbar spinal canal stenosis. Patients who were diagnosed as lumbar spinal canal stenosis might have acromegalic signs if they were relatively young.