e0273 Relationship of peripheral arterial disease, chronic kidney disease, and mortality in Chinese hypertensive patients

This study aimed to investigate the associations of chronic kidney disease (CKD), Peripheral arterial disease (PAD) and their combined effect with all-cause and Cardiovascular disease (CVD) mortality in Chinese hypertensive patients. Chinese ankle brachial index (ABI) cohort study including 2992 hypertensive patients aged 35 years or older were enrolled in 2004 and implemented the follow-up visit in 2007. 2505 participants completed baseline and follow-up data. Glomerular filtration rate (GFR) was estimated using the Modification of Diet in Renal Disease equation. ABI was calculated at baseline by measuring systolic pressures on bilateral brachial and tibial arteries. Mortality surveillance was completed from December 2007 to February 2008. Survival analysis was used to compare survival rate in different CKD/PAD groups. The RR of death from all-cause and CVD were adjusted for potential confounders using a Cox regression model. The prevalence of PAD in hypertensive patients with and without CKD was 43.1% and 22.8%, with significant difference between them (p