Successful use of combination antifungal therapy in the treatment of coccidioides meningitis.

Coccidioidal meningitis is a highly lethal condition With a high morbidity and relapse rate caused by Coccidioides immitis. 1 This case report highlights the difficulty in diagnosing and treating coccidioidal meningltis, and discusses a novel combination antifungal therapy (voriconazole and liposomal amphotericin B), which was used to treat this patient.