POST COITAL ALLERGY – A CASE REPORT OF POST ORGASMIC ILLNESS SYNDROME

The post-orgasmic illness syndrome (POIS) is a rare, but debilitating cluster of symptoms, occurring after ejaculation. The clinical case presented is a male patient, his complains started after ejaculation, four years ago, with flu-like symptoms, feverishness and sweating, brain fog, muscle pain and heavy legs, followed by concentration and attention difficulties and irritation. This status last for about 5 to 7 days, disappear spontaneously after 3 days and reappear after the next ejaculation. This postcoital illness was worsening during the years. The clinical assessment and differentiation of the diagnosis was difficult and consisted in several clinical criteria, a functional test and allergy valuation. The combination of symptoms and pathophysiological mechanisms pointed to other sex related allergies, such as seminal plasma protein allergy.