Synthesis of cis‐4a(S),8a(R)‐Perhydro‐6(2H)‐Isoquinolinones from Quinine: 4a(S), 8a(R)‐2‐Benzoyloctahydro‐6(2H)‐Isoquinolinone

Synthesis of cis-4a(S),8a(R)-perhydro-6(2H)-isoquinolinones from quinine: 4a(S), 8a(R)-2-benzoyloctahydro-6(2H)-isoquinolinone intermediate: Quininone intermediate: meroquinene tert-butyl ester intermediate: benzamide intermediate: 4a(S),8a(R)-2-Benzoyl-1,3,4,4a,5,8a-hexahydro-6(2H)-isoquinolinone intermediate: 4a(S),8a(R)-2-Benzoyloctahydro-6(2H)-isoquinolinone Keywords: acylation; addition, to CC; cleavage, oxidative; cyclization, condensation; cyclization, miscellaneous; hydrolysis, esters and lactones; oxidation, CHOH  CO; oxidation, miscellaneous; reduction, CC  HCCH; ring opening reactions