TLR4 −2242 T→C variant increases transcriptional activity of its promoter

Wang Yongtang,Jiang Jianxin,Liu Qing,Duan Zhaoxia,Gu Wei,Zeng Ling,Chen Kehong

TLR4 −2242 T→C variant increases transcriptional activity of its promoter

2009

Wang Yongtang
Jiang Jianxin
Liu Qing
Duan Zhaoxia
Gu Wei
Zeng Ling
Chen Kehong

Objective To investigate the effects of −2242, −1892 and −1837 single nucleotide polymorphisms (SNPs) on toll-like receptor 4 (TLR4) promoter activity.

Keywords:

Promoter activity
Molecular biology
TLR4
Single-nucleotide polymorphism
Medicine
Receptor
Genetics
transcriptional activity
Diabetes mellitus

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