Preparation of azithromycin in its form crystal dihydrate.
2002
The invention describes a process in which the final product is obtained by crystallization from a solution of azithromycin in Terc. Butanol, either by adding water, or by adding that solution onto a mixture of petroleum / water ether. The invention describes analytical methods for differentiating non-crystalline forms and crystallized azithromycin dihydrate.
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