Research progress of PET molecular imaging in rimmed vacuolar myopathy

Rimmed vacuole myopathy is a group of disease with characteristic myopathological features, which including deposition of abnormal proteins, such as β-amyloid protein (Aβ) and phosphorylated tau proteins etc. In recent years, positron emission tomography (PET) has been widely used in the imaging diagnosis of Alzheimer's disease (AD) due to the development of molecular imaging technology. Recently, some studies have indicated that molecular imaging PET can also show the abnormal deposition proteins in muscles, which is helpful for the early diagnosis and differential diagnosis of rimmed vacuolar myopathy, and provides a new application for PET. The application directions of PET in rimmed vacuolar myopathy were reviewed in this article, in order to provide a reference base for the implementation of clinical work. DOI: 10.11855/j.issn.0577-7402.2021.08.14