Sjogren's Syndrome and Pernicious Anaemia

We describe seven patients (five females and two males) with pernicious anaemia and Sjogren's syndrome. The diagnosis of pernicious anaemia was confirmed by bone marrow aspiration and a Schilling's test. Sjogren's syndrome was diagnosed by the Schirmer-I tear test, salivary gland scintigraphy, minor salivary gland biopsy and determination of lacrimal lysozyme. We have reviewed the literature and found few cases reported of the association of these two diseases.