Gene transduction method with nano granule as carrier based on ultrasonic intervention guiding
2005
A gene transduction method ultrasonic-based, which using the nano particulate as the carrier. It consists of animal transgenic gene method and plant transgenic gene method. The outer gene joins with the particulate with the effect of static form together to form the gene carrier, which can protect the DNA being broken by ultrasonic. The ultrasonic synchronously give effect to particulate gene carrier, cells, organize and apparatus, the carrier can run efficiently through the short period alleyway of cell wall, cell film, core film cell, enables the outer gene constructs with the gene group in cell. This method has a high efficiency, and is provided with convenient manipulation, high efficiency, no request of differential function e.g. other merits. It can be applied widely to these range, animal and plant transgenic technology and genic cure of human being.
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