A research of the relationship between insulin resistance and lacunar infarction.

Objective To study the relationship between insulin resistance and lacunar infarction,then to discuss its possible mechanisms.Methods 47patients with stroke were divided into lacuna infarction group(LI,23cases) and non-lacuna group(NLI,24 cases).The normal control group had 24 people.Their fasting plasma glucoses,serum insulin,serum lipids were measured and their insulin sensitivity indexes(ISI) calculated.Results ISI of LI group were significantly lower than NLI group and normal control group(P0.05).The plasma level of TG and insulin in LI group were significantly higher than those in two other groups(P0.05).Conclusion There is an strong relationship between IR and lacuna infarction.