Production of 211At using the JSW BC3015 at the University of Pennsylvania

Using 211At for targeted radiotherapy has long been discussed. We describe using 30 MeV α-particle beams accelerated with the Japan Steel Works, BC3015 cyclotron at the University of Pennsylvania with the goal of 211At-MABG production. Target manufacturing and cooling is discussed. Active beam monitoring using a beam-profile monitor ensures a uniform particle profile across the target. A head-on irradiation geometry is used. Cross calibrations and thick target yields will be presented. Extracted amounts of 211At from the target, and limits to the production of 210At and our MABG labeling results and yields will be discussed.