13. Prevention of Recurrent Mucinous Borderline Ovarian Tumor with Aromatase Inhibitor

Abstract Background Aromatase inhibitors (AIs) are utilized for estrogen-modulated conditions. Some borderline ovarian tumors (BOT) express estrogen receptors. We present two cases of progression from mucinous cystadenoma to mucinous BOT (mBOT) after prior cystectomies in whom an AI was used with recurrence prevention. Case Two patients underwent laparoscopic ovarian cystectomy for mucinous cystadenoma. Serial imaging demonstrated recurrent ovarian cysts for which both underwent fertility sparing surgery (FSS) with ovarian cystectomy for mBOT. Both patients were initiated on an AI and have been without recurrence. Summary And Conclusion BOT predominantly occur in reproductive aged females. FSS with cystectomy is an option, but recurrence occurs in 12-36% of cases. The use of AI in prevention of recurrent BOT shows promise, and more studies are needed to explore this treatment.