Alzheimer disease, from molecular biology to therapy.

Part 1 Pathological basis of therapy in Alzheimer's disease: criteria for diagnosis of Alzheimer's disease neuropathology of Alzheimer's disease cell death - excitotoxins, apoptosis and hypometabolism. Part 2 The cholinergic system in brain: treatment of Alzheimer disease cholinesterase inhibitors in Alzheimer disease treatment. Part 3 Nicotinic and muscarnic cholinergic agonists: nicotinic agonists the potential for anti-inflammatory therapy. Part 4 Development of new therapies in Alzheimer's disease: design of clinical trials SPECT and PET. Part 5 Social issues in Alzheimer's disease: legal and ethical issues socio-economic aspects of Alzheimer disease treatment.