Synthesis and antibacterial activity of potent heterocyclic oxazolidinones and the identification of RBx 8700
2007
Abstract Several potent oxazolidinone antibacterial agents were obtained by systematic modification of the linker between the five-membered heterocycle and the piperazinyl ring of RBx 7644 (Ranbezolid, 1 ) and its thienyl analogue 2 , leading to the identification of an expanded spectrum compound RBx 8700 ( 6b ).
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