Cremophor-emulgens tartalmu kremek gyogyszerleadasanak vizsgalata

: Release of poorly soluble drug from several creams containing 50-75% water was investigated and the dependence of liberation on the emulsifier- and water content was established. The emulsifier content vs. liberation function can be described with a maximum curve, the relationship between drug release and viscosity can be characterized by a reciprocal or a logarithmic function.