[The clinical use of immunosorption: problems and perspectives].

: The data concerning clinical use of extracorporeal immunoadsorption are summarized. At present, broad use of this therapeutic approach is hampered by several technological and medical problems such as incomplete biocompatibility of carrier, pyrogenic reactions, ligand "leakage" and rebound phenomena. However, the technology of ex vivo removal is much more developed, than the fundamental knowledge of relevant target substance to be removed in specific clinical situation. The appropriate denomination of such "targets" should provide this method with a wide application field in clinical medicine.