CHARACTERIZE THE EFFECTS OF A GLUCOSYLCERAMIDE INHIBITOR ON OBESITY

Proteomic data acquisition utilized data independent analysis (DIA) with a nanoscale LC nanoACQUITY system directly interfaced to a hybrid IMS-oaToF Synapt G2-Si. Lipidomic measurements were conducted using a Xevo G2-S mass spectrometer, operating in DIA. Ion mobility (IM) was used in conjunction with the proteomic acquisition schema, illustrated in Figure 2.