124 cases of hemolytic diseases in newborn infants other than ABO and Rhesus D observed in the Blood Transfusion Center of Lyon between 1970 and 1982

: Between 1970 and 1982, 124 cases of hemolytic diseases of the newborn due to antigens other than A, B and Rhesus-D were observed in the Blood Bank of Lyon (France). These cases represent 10,3% of all the hemolytic diseases of the newborn (ABO excluded). This percentage has raised during this period: 2,1% in 1970 until 39,2% in 1982. The variation is due both to the fall of the Rhesus-D hemolytic diseases and to the raise of non Rhesus-D hemolytic diseases. The alloantibody titer is not a good criteria in order to predict the anemia level of the newborn but the amniotic fluid delta OD 450 is satisfactory whatever the alloimmunisation is.