Higher Mucosal Healing with Tumor Necrosis Factor Inhibitors in Combination with Thiopurines Compared to Methotrexate in Crohn’s Disease

Abhinav Vasudevan,Ajay Raghunath,Shane N. Anthony,Cian Scanlon,Miles Sparrow,Peter R. Gibson,Daniel R. van Langenberg

Higher Mucosal Healing with Tumor Necrosis Factor Inhibitors in Combination with Thiopurines Compared to Methotrexate in Crohn’s Disease

2018

Abhinav Vasudevan
Ajay Raghunath
Shane N. Anthony
Cian Scanlon
Miles Sparrow
Peter R. Gibson
Daniel R. van Langenberg

Background The differential impact of anti-tumor necrosis factor (anti-TNF) therapy with methotrexate versus thiopurine co-therapy on endoscopic remission remains uncertain.

Keywords:

Thiopurine methyltransferase
Endocrinology
Medicine
Internal medicine
General surgery
Azathioprine
Infliximab
Tumor necrosis factor alpha
Mercaptopurine
Methotrexate
Adalimumab
Crohn's disease
Gastroenterology
Adverse effect

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