Recent Advances in Functionalization of α‐C(sp3)–H Centres in Inactivated Ethers through Cross Dehydrogenative Coupling

Carbon–carbon and carbon–heteroatom bond construction through oxidative carbon–hydrogen bond activation has attracted much attention in synthetic organic chemistry. Recently, a variety of reactions of inactivated cyclic ethers (THF, THP and dioxane) and acyclic ethers with various coupling partners have been reported. Despite the absence of phenyl rings and high oxidation potentials, these ethers worked efficiently under oxidative conditions. This review focusses on recent reports of C–C and C–heteroatom bond formation in these cyclic and acyclic ethers through cross dehydrogenative coupling.