Medical hot melt pressure sensitive adhesive substrate and preparation method thereof

The invention discloses a medical hot melt pressure sensitive adhesive substrate and a preparation method thereof, and belongs to the technical field of hot melt adhesives. According to the hot melt pressure sensitive adhesive substrate, 40 to 60 weight parts of epoxidation modified styrene-dialkene-styrene block copolymer thermoplastic elastomer is taken as a main body, partial double bonds of the copolymer are converted into epoxide groups, 30 to 70 weight parts of tackifier, 30 to 60 weight parts of plasticizer and 1 to 10 weight parts of antioxidant are added, and a hot melt pressure sensitive adhesive is prepared and is stirred to be fused under the protection of nitrogen. The hot melt pressure sensitive adhesive is transparent, high in polarity and medicine-loading rate, has moisture-penetrability, is attached to skin to ensure that the skin is comfortable, and contains 100 percent of solid content without solvent.