BIOMEMBRANE-GATED CARBON NANOTUBE TRANSISTOR AS A SENSING PLATFORM

Here we demonstrate the biomembrane-gated carbon nanotube transistor as a new sensing platform. The simple way to pattern SLBs onto desired area of CNT films using microfluidic channels is described. Integrated systems in which allsemiconducting nanotube network transistors are coated directly with lipid bilayers and electrical modulation of this device by lipid bilayer and ion channels are demonstrated. This new system forms a mechanically robust, stable platform for various sensing applications. Finally, in contrast to all previous studies using nanotubes for membrane interrogation, we use a simple, robust fabrication process based on printable semiconducting nanotube ink, which is compatible with massmanufacturing in roll-to-roll, flexible electronic applications. This will allow direct translation of the technology into a low cost, next generation measurement system for electrophysiology. This approach will find broad applications in electrophysiology and membrane protein studies.