Legionella pneumophila LPS to evaluate urinary antigen tests

Anne-Gaëlle Ranc,Margot Carpentier,L. Béraud,Ghislaine Descours,Christophe Ginevra,Elodie Maisonneuve,Julien Verdon,Jean Marc Berjeaud,Gerard Lina,Sophie Jarraud

Legionella pneumophila LPS to evaluate urinary antigen tests

2017

Anne-Gaëlle Ranc
Margot Carpentier
L. Béraud
Ghislaine Descours
Christophe Ginevra
Elodie Maisonneuve
Julien Verdon
Jean Marc Berjeaud
Gerard Lina
Sophie Jarraud

Three urinary antigen tests were compared using purified Legionella pneumophila (Lp) LPS. For Lp serogroup1, Sofia®FIA and Binax®EIA limits of detection (LOD) were similar; that of BinaxNOW® lower. For all tests the LOD was higher with LPS from non-Pontiac compared to Pontiac-strains. The LOD was variable for other Lp serogroups.

Keywords:

Microbiology
Virology
Biology
Antigen
Legionella pneumophila
Urinary system
Legionnaires' disease
Immunoenzyme techniques

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