PROSPECTIVE STUDY OF ASPIRIN FOR THROMBOEMBOLISM PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY

2018 
Objectives: To evaluate the effectiveness of aspirin as prophylaxis for deep venous thrombosis (DVT) in patients undergoing total hip arthroplasty (THA), and to analyze the incidence of bleeding during the post-operative period. Methods: This prospective study carried out in 2017 consisted of 37 patients indicated for THA with high risk for DVT. Immediately after the procedure, aspirin, elastic compression socks and early deambulation were initiated. Doppler ultrasound was performed in the legs 6 days and 6 weeks post-procedure to rule out venous thromboembolism. Hematometric variables and clinical criteria were used to detect bleeding. Resultados: No 6o dia apos o procedimento, a incidencia de TEV (tromboembolismo venoso) foi 21,6% e na 6a semana houve uma reducao para 8,1% (p = 0,102). Apenas 2,7% foram diagnosticados com TVP tanto no 6o dia como na 6a semana. No pos-operatorio imediato houve uma reducao da hemoglobina (p < 0,001), contrastando com a sexta semana de pos-operatorio, quando esses niveis se elevaram para os niveis basais. Conclusion: Aspirin was an effective chemical prophylaxis for venous thromboembolism in high-risk patients who underwent THA. There was no clinical record of postoperative bleeding and hematometric levels suggested that there was no chronic bleeding. Level of Evidence II; Prospective study.
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