Euclidean D-branes in Type IIB string theory on Calabi-Yau threefolds.

We compute the contribution of Euclidean D-branes in type IIB string theory on Calabi-Yau threefolds to the metric on the hypermultiplet moduli space in the large volume, weak coupling limit. Our results are in perfect agreement with the predictions based on S-duality, mirror symmetry and supersymmetry.