Osteoporosis in Rheumatoid Arthritis: Epidemiology, Pathogenesis and Management

Rheumatoid arthritis (RA) is a common inflammatory arthropathy of unknown etiology. Its radiological features are well described, which include juxtaarticular osteoporosis and bone erosion in the affected joints. In rheumatology practice, RA and use of oral steroid are the commonest causes for secondary generalized osteoporosis. Over the past decade, there is increasing focus on the relationship between RA and osteoporosis. This is because of the significant morbidity and mortality associated with osteoporotic fractures. The outcome of osteoporosis would certainly be improved if physicians can appreciate and offer appropriate management of this condition in RA patients.