Abstract 17751: Low Appendicular Skeletal Muscle Mass is Associated With High Coronary Plaque Complexity in Patients With ST-segment Elevation Myocardial Infarction

Introduction: Loss of skeletal muscle mass is associated with diabetes, insulin resistance, inflammation, and generalized atherosclerosis. The angiographic complexity of coronary artery disease can predict outcomes in patients undergoing percutaneous coronary intervention. However, the relationship between skeletal muscle mass and ST-segment elevation myocardial infarction (STEMI) remains undetermined. Hypothesis: We assessed the hypothesis that low appendicular skeletal muscle mass index (ASMI) is associated with high coronary plaque complexity in patients with STEMI. Methods: We enrolled consecutive 112 patients with STEMI (age 64±12, male 87.5%) in this study. Appendicular skeletal muscle mass was estimated from dual-energy X-ray absorptiometry (DXA) scan before discharge and ASMI was defined as appendicular skeletal muscle mass divided by height squared (kg/m2). ASMI was dichotomized according to the Asia Working Group for Sarcopenia criteria, which determined low (<7.0 kg/m2 for men and <5.4 kg/m2 fo...